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Proceedings Paper

Dual modality fluorescence and reflectance hyperspectral imaging: principle and applications
Author(s): Matthew E. Martin; Musundi B. Wabuyele; Masoud Panjehpour; Mary N. Phan; Bergein F. Overholt; Robert C. DeNovo; Tamberlyn Moyers; Seong Gon Song; Tuan Vo-Dinh
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Paper Abstract

We present the principles and applications of our dual-modality fluorescence and reflectance hyperspectral imaging (DMHSI) system. In this paper we report on background work done using laser induced fluorescence (LIF) by the group in the early detection of esophageal cancer. We then demonstrate the capabilities of our new DMHSI system. The system consists of a laser, endoscope, AOTF, and two cameras coupled with optics and electronics. Preliminary results, performed on mouse tissue, show that the system can delineate normal and malignant tissue regions in real-time.

Paper Details

Date Published: 1 April 2005
PDF: 7 pages
Proc. SPIE 5692, Advanced Biomedical and Clinical Diagnostic Systems III, (1 April 2005); doi: 10.1117/12.604445
Show Author Affiliations
Matthew E. Martin, Oak Ridge National Lab. (United States)
Musundi B. Wabuyele, Oak Ridge National Lab. (United States)
Masoud Panjehpour, Thompson Cancer Ctr.. (United States)
Mary N. Phan, Thompson Cancer Ctr.. (United States)
Bergein F. Overholt, Thompson Cancer Ctr.. (United States)
Robert C. DeNovo, Univ. of Tennessee/Knoxville (United States)
Tamberlyn Moyers, Univ. of Tennessee/Knoxville (United States)
Seong Gon Song, Univ. of Tennessee/Knoxville (United States)
Tuan Vo-Dinh, Oak Ridge National Lab. (United States)

Published in SPIE Proceedings Vol. 5692:
Advanced Biomedical and Clinical Diagnostic Systems III
Tuan Vo-Dinh; Warren S. Grundfest; David A. Benaron; Gerald E. Cohn, Editor(s)

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