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Proceedings Paper

Terahertz signature characterization of bio-simulants
Author(s): Alexander J. Majewski; Peter Miller; Rene Abreu; Jeffrey Grotts; Tatiana Globus; Elliott Brown
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Paper Abstract

Collaboration with the University of Virginia (UVa) and the University of California, Santa Barbara (UCSB) has resulted in the collection of signature data in the THz region of the spectrum for ovalbumin, Bacillus Subtilis (BG) and RNA from MS2 phage. Two independent experimental measurement systems were used to characterize the bio-simulants. Prior to our efforts, only a limited signature database existed. The goal was to evaluate a larger ensemble of biological agent simulants (BG, MS2 and ovalbumin) by measuring their THz absorption spectra. UCSB used a photomixer spectrometer and UVa a Fourier Transform spectrometer to measure absorption spectra. Each group used different sample preparation techniques and made multiple measurements to provide reliable statistics. Data processing culminated in applying proprietary algorithms to develop detection filters for each simulant. Through a covariance matrix approach, the detection filters extract signatures over regions with strong absorption and ignore regions with large signature variation (noise). The discrimination capability of these filters was also tested. The probability of detection and false alarm for each simulant was analyzed by each simulant specific filter. We analyzed a limited set of Bacillus thuringiensis (BT) data (a near neighbor to BG) and were capable of discriminating between BT and BG. The signal processing and filter construction demonstrates signature specificity and filter discrimination capabilities.

Paper Details

Date Published: 18 May 2005
PDF: 11 pages
Proc. SPIE 5790, Terahertz for Military and Security Applications III, (18 May 2005); doi: 10.1117/12.603658
Show Author Affiliations
Alexander J. Majewski, Goodrich Corp. (United States)
Peter Miller, Goodrich Corp. (United States)
Rene Abreu, Goodrich Corp. (United States)
Jeffrey Grotts, Goodrich Corp. (United States)
Tatiana Globus, Univ. of Virginia (United States)
Elliott Brown, Univ. of California/Santa Barbara (United States)

Published in SPIE Proceedings Vol. 5790:
Terahertz for Military and Security Applications III
R. Jennifer Hwu; Dwight L. Woolard; Mark J. Rosker, Editor(s)

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