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Proceedings Paper

Improvements in self-assembled optical fiber-based biosensors
Author(s): Richard O. Claus; Francisco J. Arregui; Ignacio R. Matias; Hang Ruan; Yuhong Kang; Theodore Distler; Jeffrey Mecham; Bradley Davis
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Paper Abstract

This paper describes improvements that have been made in optical fiber biosensors based on thin films deposited onto the ends of optical fiber waveguides using molecular-level self-assembly processes. The properties of the sensor films may be varied by controlling both the chemistry and the morphology and ordering of the films during their fabrication. For example, multilayer segments of films having different indices of refraction may be deposited to form quarter wavelength stack filters whose reflection properties change as a function of concentration of target chemical that modifies the index of the outermost layer or layers. Prior work has shown that by using different chemicals in the self-assembled layers, correspondingly different target chemicals may be detected. These have included water vapor, ammonia, dichloromethane and others. Improvements have been made in the range of index of refraction that may be achieved in the individual layer segments, specifically over the range of 1.2 to 1.8 at visible and near-infrared wavelengths. This paper shows how such an improvement in index difference influences the minimum detectable chemical concentration difference detectable using this approach.

Paper Details

Date Published: 23 March 2005
PDF: 6 pages
Proc. SPIE 5691, Optical Fibers and Sensors for Medical Applications V, (23 March 2005); doi: 10.1117/12.602109
Show Author Affiliations
Richard O. Claus, Virginia Polytechnic Institute and State Univ. (United States)
NanoSonic, Inc. (United States)
Francisco J. Arregui, Univ. Publica de Navarra (Spain)
Ignacio R. Matias, Univ. Publica de Navarra (Spain)
Hang Ruan, NanoSonic, Inc. (United States)
Yuhong Kang, NanoSonic, Inc. (United States)
Theodore Distler, NanoSonic, Inc. (United States)
Jeffrey Mecham, NanoSonic, Inc. (United States)
Bradley Davis, NanoSonic, Inc. (United States)

Published in SPIE Proceedings Vol. 5691:
Optical Fibers and Sensors for Medical Applications V
Israel Gannot, Editor(s)

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