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Proceedings Paper

From lab-on-a-chip to lab-in-a-cell
Author(s): Helene Andersson; Albert van den Berg
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Paper Abstract

There are many efforts today trying to mimic the properties of single cells in order to design chips that are as efficient as cells. However, cells are nature’s nanotechnology engineering at the scale of atoms and molecules. Therefore, it might be better to vision a microchip that utilizes a single cell as experimentation platform. A novel, so-called Lab-in-a-Cell (LIC) concept is described, where advantage is taken of micro/nanotechnological tools to enable precise control of the biochemical cellular environment and possibility to analyze the composition of single cells. This is followed by a review on the present chip solutions for single cell handling and analysis.

Paper Details

Date Published: 22 January 2005
PDF: 12 pages
Proc. SPIE 5718, Microfluidics, BioMEMS, and Medical Microsystems III, (22 January 2005); doi: 10.1117/12.601553
Show Author Affiliations
Helene Andersson, Univ. Twente (Netherlands)
Royal Institute of Technology (Sweden)
Albert van den Berg, Univ. Twente (Netherlands)

Published in SPIE Proceedings Vol. 5718:
Microfluidics, BioMEMS, and Medical Microsystems III
Ian Papautsky; Isabelle Chartier, Editor(s)

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