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Proceedings Paper

Surfactant-assisted synthesis of water-soluble and biocompatible semiconductor quantum dot-micelles
Author(s): Hongyou Fan; Erik W. Leve; Chessa Scullin; David Tallant; Michael C. Wilson; C. Jeffrey Brinker
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Paper Abstract

We report a simple and rapid method to synthesize water-soluble and biocompatible fluorescent quantum dot (QD)-micelles by encapsulation of monodisperse, hydrophobic QDs inside surfactant/lipid micelles. Analysis of UV-vis spectra, transmission electron microscopy, and photo luminescence spectra indicate that the water-soluble semiconductor QD-micelles are monodisperse and retain the optical properties of the original hydrophobic QDs. The QD-micelles were shown to be biocompatible and exhibited little or no aggregation when taken up by cultured rat hippocampal neurons.

Paper Details

Date Published: 28 April 2005
PDF: 9 pages
Proc. SPIE 5705, Nanobiophotonics and Biomedical Applications II, (28 April 2005); doi: 10.1117/12.601511
Show Author Affiliations
Hongyou Fan, Sandia National Labs. (United States)
The Univ. of New Mexico (United States)
Erik W. Leve, The Univ. of New Mexico (United States)
Chessa Scullin, The Univ. of New Mexico (United States)
David Tallant, Sandia National Labs. (United States)
Michael C. Wilson, The Univ. of New Mexico (United States)
C. Jeffrey Brinker, Sandia National Labs. (United States)
The Univ. of New Mexico (United States)

Published in SPIE Proceedings Vol. 5705:
Nanobiophotonics and Biomedical Applications II
Alexander N. Cartwright; Marek Osinski, Editor(s)

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