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Proceedings Paper

Application of atomic force microscope to the study of bio-cells
Author(s): Bernhard R. Tittmann; Jikai Du; Anne Ebert; Brian Piccione
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Paper Abstract

Ultrasonic atomic force microscopy (U-AFM) was used to image the elastic properties of hamster kidney (BHK) cells. Force-distance curves and finite element analysis were also used in this work assist in the description of the U-AFM images. These tools helped explain the differences in contrast seen from the center to the edge of the cell. The explanation of the U-AFM image contrast will lead to more analytical tools to investigate both nonviable and viable materials. Improvement of our system for living cell (in a culture) imaging is also discussed.

Paper Details

Date Published: 9 May 2005
PDF: 8 pages
Proc. SPIE 5768, Health Monitoring and Smart Nondestructive Evaluation of Structural and Biological Systems IV, (9 May 2005); doi: 10.1117/12.598871
Show Author Affiliations
Bernhard R. Tittmann, The Pennsylvania State Univ. (United States)
Jikai Du, The Pennsylvania State Univ. (United States)
Anne Ebert, The Pennsylvania State Univ. (United States)
Brian Piccione, The Pennsylvania State Univ. (United States)


Published in SPIE Proceedings Vol. 5768:
Health Monitoring and Smart Nondestructive Evaluation of Structural and Biological Systems IV
Tribikram Kundu, Editor(s)

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