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Proceedings Paper

Estimation of regional lung expansion via 3D image registration
Author(s): Yan Pan; Dinesh Kumar; Eric A. Hoffman; Gary E. Christensen; Geoffrey McLennan; Joo Hyun Song; Alan Ross; Brett A. Simon; Joseph M. Reinhardt
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Paper Abstract

A method is described to estimate regional lung expansion and related biomechanical parameters using multiple CT images of the lungs, acquired at different inflation levels. In this study, the lungs of two sheep were imaged utilizing a multi-detector row CT at different lung inflations in the prone and supine positions. Using the lung surfaces and the airway branch points for guidance, a 3D inverse consistent image registration procedure was used to match different lung volumes at each orientation. The registration was validated using a set of implanted metal markers. After registration, the Jacobian of the deformation field was computed to express regional expansion or contraction. The regional lung expansion at different pressures and different orientations are compared.

Paper Details

Date Published: 14 April 2005
PDF: 12 pages
Proc. SPIE 5746, Medical Imaging 2005: Physiology, Function, and Structure from Medical Images, (14 April 2005); doi: 10.1117/12.596617
Show Author Affiliations
Yan Pan, Univ. of Iowa (United States)
Dinesh Kumar, Univ. of Iowa (United States)
Eric A. Hoffman, Univ. of Iowa (United States)
Gary E. Christensen, Univ. of Iowa (United States)
Geoffrey McLennan, Univ. of Iowa (United States)
Joo Hyun Song, Univ. of Iowa (United States)
Alan Ross, Univ. of Iowa (United States)
Brett A. Simon, Johns Hopkins Medical Institute (United States)
Joseph M. Reinhardt, Univ. of Iowa (United States)


Published in SPIE Proceedings Vol. 5746:
Medical Imaging 2005: Physiology, Function, and Structure from Medical Images
Amir A. Amini; Armando Manduca, Editor(s)

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