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Proceedings Paper

MRI and SPECT fusion for epilepsy lateralization
Author(s): Kourosh Jafari-Khouzani; Hamid Soltanian-Zadeh; Kost Elisevich
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Paper Abstract

This paper presents a study on the SPECT images of the brain with the aim of determining the hippocampus abnormality and consequently applying timely treatment. Intensity and volume features of the hippocampus from brain MRI have been shown to be useful in detecting the abnormal hippocampus in TLE. In this study, we evaluate the intensity information of the SPECT images of the brain for the purpose of early detection of abnormal hippocampus, before the brain tissue is damaged and MRI features change. The hippocampi are segmented manually by an expert from T1-weighted MR images. The segmented regions are mapped on the corresponding SPECT images using the mutual information technique. The mean and standard deviation of the hippocampi from SPECT images are used to determine abnormal hippocampus. The experimental results show that SPECT images analyzed along with MRI generate quantitative information useful for the treatment and evaluation of epileptic patients.

Paper Details

Date Published: 14 April 2005
PDF: 8 pages
Proc. SPIE 5746, Medical Imaging 2005: Physiology, Function, and Structure from Medical Images, (14 April 2005); doi: 10.1117/12.596401
Show Author Affiliations
Kourosh Jafari-Khouzani, Wayne State Univ. (United States)
Henry Ford Health System (United States)
Hamid Soltanian-Zadeh, Henry Ford Health System (United States)
Univ. of Tehran (Iran)
Kost Elisevich, Henry Ford Health System (United States)


Published in SPIE Proceedings Vol. 5746:
Medical Imaging 2005: Physiology, Function, and Structure from Medical Images
Amir A. Amini; Armando Manduca, Editor(s)

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