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Proceedings Paper

A statistical model-based approach for the automatic quantitative analysis of perfusion gated SPECT studies
Author(s): Sebastian Ordas; Santiago Aguade; Joan Castell; Alejandro F. Frangi
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Paper Abstract

In this paper we present a statistical model-based approach to three-dimensional (3D) analysis of gated SPECT perfusion studies. By means of a 3D Active Shape Model (3D-ASM) segmentation algorithm, delineations of the endo- and epicardial borders of the left ventricle are obtained, in all temporal phases and image slices of the study. Prior knowledge was captured from a training set of cardiac MRI and SPECT studies, from which geometrical (shape) and grey-level (appearance) statistical models were built. From the fitted shape, a truly 3D representation of the left ventricle, a series of global and regional functional parameters can be assessed. A myocardial center surface representation is built on top of which scalar maps of perfusion, thickness or motion can be depicted. Preliminary results were quite encouraging, suggesting that statistical model-based segmentation may serve as a robust technique for routine use.

Paper Details

Date Published: 14 April 2005
PDF: 11 pages
Proc. SPIE 5746, Medical Imaging 2005: Physiology, Function, and Structure from Medical Images, (14 April 2005); doi: 10.1117/12.595897
Show Author Affiliations
Sebastian Ordas, Univ. Pompeu Fabra (Spain)
Santiago Aguade, Hospital Univ. Vall d'Hebron (Spain)
Joan Castell, Hospital Univ. Vall d'Hebron (Spain)
Alejandro F. Frangi, Univ. Pompeu Fabra (Spain)

Published in SPIE Proceedings Vol. 5746:
Medical Imaging 2005: Physiology, Function, and Structure from Medical Images
Amir A. Amini; Armando Manduca, Editor(s)

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