Share Email Print

Proceedings Paper

Changes in interhemispheric motor connectivity after muscle fatigue
Author(s): Scott Peltier; Stephen M. LaConte; Dmitriy Niyazov; Jing Liu; Vinod Sahgal; Guang Yue; Xiaoping Hu
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Synchronized oscillations in resting state timecourses have been detected in recent fMRI studies. These oscillations are low frequency in nature (< 0.08 Hz), and seem to be a property of symmetric cortices. These fluctuations are important as a potential signal of interest, which could indicate connectivity between functionally related areas of the brain. It has also been shown that the synchronized oscillations decrease in some spontaneous pathological states. Thus, detection of these functional connectivity patterns may help to serve as a gauge of normal brain activity. The cognitive effects of muscle fatigue are not well characterized. Sustained fatigue has the potential to dynamically alter activity in brain networks. In this work, we examined the interhemispheric correlations in the left and right primary motor cortices and how they change with muscle fatigue. Resting-state functional MRI imaging was done before and after a repetitive unilateral fatigue task. We find that the number of significant correlations in the bilateral motor network decreases with fatigue. These results suggest that resting-state interhemispheric motor cortex functional connectivity is affected by muscle fatigue.

Paper Details

Date Published: 14 April 2005
PDF: 5 pages
Proc. SPIE 5746, Medical Imaging 2005: Physiology, Function, and Structure from Medical Images, (14 April 2005); doi: 10.1117/12.595628
Show Author Affiliations
Scott Peltier, Emory Univ./Georgia Tech (United States)
Stephen M. LaConte, Emory Univ./Georgia Tech (United States)
Dmitriy Niyazov, Emory Univ./Georgia Tech (United States)
Jing Liu, Cleveland Clinic Foundation (United States)
Vinod Sahgal, Cleveland Clinic Foundation (United States)
Guang Yue, Cleveland Clinic Foundation (United States)
Xiaoping Hu, Emory Univ./Georgia Tech (United States)

Published in SPIE Proceedings Vol. 5746:
Medical Imaging 2005: Physiology, Function, and Structure from Medical Images
Amir A. Amini; Armando Manduca, Editor(s)

© SPIE. Terms of Use
Back to Top