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Proceedings Paper

Correlating aneurysm growth to hemodynamic parameters: the case of a patient-specific anterior communicating artery aneurysm
Author(s): Prem Venugopal; Hui Chen; Gary Duckwiler; Richard Kemkers; Pablo Villablanca; Fernando Vinuela; Hein Haas; Daniel Valentino
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Paper Abstract

Numerical simulations of pulsatile blood flow were conducted in a patient-specific model of an anterior communicating artery aneurysm that was found to grow over time. The effect of changes in inflow parameters on the numerical simulation results was also investigated since patient-specific velocity measurements were not available to be used as inflow conditions. It was found that shear stress distribution in the region where aneurysm growth is observed is sensitive to how flow rates are distributed in the A1 segments of the anterior cerebral arteries. The impingement location for the blood stream coming from the left anterior cerebral artery was also sensitive to the flow rate distribution in the A1 segments. Further, it was found that changing the inflow Reynolds number without altering the flow rate distribution in the A1 segments also affects the shear stress distribution on the aneurysm surface. These results suggest that at least for the anterior communicating artery aneurysm considered in this study, knowledge of the actual velocities in the A1 segments is necessary to make judgments on the hemodynamic parameter responsible for the aneurysm's growth.

Paper Details

Date Published: 14 April 2005
PDF: 12 pages
Proc. SPIE 5746, Medical Imaging 2005: Physiology, Function, and Structure from Medical Images, (14 April 2005); doi: 10.1117/12.595508
Show Author Affiliations
Prem Venugopal, Philips Medical Systems (United States)
Hui Chen, Univ. of California/Los Angeles (United States)
Gary Duckwiler, Univ. of California/Los Angeles (United States)
Richard Kemkers, Philips Medical Systems (United States)
Pablo Villablanca, Univ. of California/Los Angeles (United States)
Fernando Vinuela, Univ. of California/Los Angeles (United States)
Hein Haas, Philips Medical Systems (United States)
Daniel Valentino, Univ. of California/Los Angeles (United States)


Published in SPIE Proceedings Vol. 5746:
Medical Imaging 2005: Physiology, Function, and Structure from Medical Images
Amir A. Amini; Armando Manduca, Editor(s)

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