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Proceedings Paper

Deformable model for 3D intramodal nonrigid breast image registration with fiducial skin markers
Author(s): Mehmet Z. Unlu; Andrzej Krol; Ioana L.. Coman; James A. Mandel; Karl G. Baum; Wei Lee; Edward D. Lipson; David H. Feiglin
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Paper Abstract

We implemented a new approach to intramodal non-rigid 3D breast image registration. Our method uses fiducial skin markers (FSM) placed on the breast surface. After determining the displacements of FSM, finite element method (FEM) is used to distribute the markers’ displacements linearly over the entire breast volume using the analogy between the orthogonal components of the displacement field and a steady state heat transfer (SSHT). It is valid because the displacement field in x, y and z direction and a SSHT problem can both be modeled using LaPlace’s equation and the displacements are analogous to temperature differences in SSHT. It can be solved via standard heat conduction FEM software with arbitrary conductivity of surface elements significantly higher than that of volume elements. After determining the displacements of the mesh nodes over the entire breast volume, moving breast volume is registered to target breast volume using an image warping algorithm. Very good quality of the registration was obtained. Following similarity measurements were estimated: Normalized Mutual Information (NMI), Normalized Correlation Coefficient (NCC) and Sum of Absolute Valued Differences (SAVD). We also compared our method with rigid registration technique.

Paper Details

Date Published: 29 April 2005
PDF: 7 pages
Proc. SPIE 5747, Medical Imaging 2005: Image Processing, (29 April 2005); doi: 10.1117/12.595420
Show Author Affiliations
Mehmet Z. Unlu, Syracuse Univ. (United States)
Andrzej Krol, Upstate Medical Univ./SUNY (United States)
Syracuse Univ. (United States)
Ioana L.. Coman, Ithaca College (United States)
Syracuse Univ. (United States)
Upstate Medical Univ./SUNY (United States)
James A. Mandel, Syracuse Univ. (United States)
Karl G. Baum, Rochester Institute of Technology (United States)
Wei Lee, Syracuse Univ. (United States)
Edward D. Lipson, Syracuse Univ. (United States)
Upstate Medical Univ./SUNY (United States)
David H. Feiglin, Upstate Medical Univ./SUNY (United States)


Published in SPIE Proceedings Vol. 5747:
Medical Imaging 2005: Image Processing
J. Michael Fitzpatrick; Joseph M. Reinhardt, Editor(s)

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