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Proceedings Paper

Relevant information retrieval and fusion of anatomic, physiologic, and metabolic neuroimaging
Author(s): Stephan G. Erberich; Jon F. Nielsen; Ashok Panigrahy; Stefan Bluml; Istvan Seri; Marvin D. Nelson
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Paper Abstract

MRI Neuroimaging provides a rich source of image content including structural (MRI, Diffusion DTI), functional (fMRI, Perfusion ASL), and metabolic (MRS) information. Today MRI capabilities allow to acquire these imaging techniques in one session in most cases. In order to be of diagnostic value, the immense and diverse data needs to be (i) automatically post-processed to extract the relevant information, e.g. 3D brain maps from 4D fMRI, and to be (ii) fused and visualized to correlate the voxel-based findings. The purpose of this study is to demonstrate the feasibility of automatic relevant information retrieval and fusion of MRI, fMRI, DTI, ASL, and MRS data of a pediatric population into a single semantic data representation. By using advanced imaging, we may able to detect a larger spectrum of abnormalities in the neonatal brain. Each imaging application, provides unique information about the physiology (fMRI, ASL), the anatomy (DTI), and the biochemistry (MRS) of the newborn brain in relation to normal development and brain injury. By being able to integrate this technology, we will be able to combine biochemical, physiologic and anatomic information which can provide unique insight about not only the normal development of the brain, but also injury of the neonatal brain.

Paper Details

Date Published: 14 April 2005
PDF: 8 pages
Proc. SPIE 5746, Medical Imaging 2005: Physiology, Function, and Structure from Medical Images, (14 April 2005); doi: 10.1117/12.595127
Show Author Affiliations
Stephan G. Erberich, Children's Hospital Los Angeles and Univ. of Southern California (United States)
Jon F. Nielsen, Children's Hospital Los Angeles and Univ. of Southern California (United States)
Ashok Panigrahy, Children's Hospital Los Angeles and Univ. of Southern California (United States)
Stefan Bluml, Children's Hospital Los Angeles and Univ. of Southern California (United States)
Istvan Seri, Children's Hospital Los Angeles and Univ. of Southern California (United States)
Marvin D. Nelson, Children's Hospital Los Angeles and Univ. of Southern California (United States)


Published in SPIE Proceedings Vol. 5746:
Medical Imaging 2005: Physiology, Function, and Structure from Medical Images
Amir A. Amini; Armando Manduca, Editor(s)

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