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Proceedings Paper

Comparison of 3D dense deformable registration methods for breath-hold reproducibility study in radiotherapy
Author(s): Vlad Boldea; David Sarrut; Christian Carrie
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Paper Abstract

Breath holding (BH) allows to immobilize organs during radiotherapy treatment of lung cancer. Deformable registration methods applied on 3D Computerized Tomography (CT) scans acquired in BH can be used to evaluate the breath holding reproducibility. Resulting 3D vector fields could then be used to adapt internal margins for each patient. In this work we compare three non-rigid registration schemes with Gaussian, linear-elastic and Nagel-Enckelmann based regularizations. As we do not dispose of gold standard, we analyze vector fields by several operators (transitivity, symmetry, volume dilatation, Jacobian). Experiments were based on clinical data sets of two patients: one with normal lung behavior and second with lung discrepancies which lead to bad BH reproducibility. Results show that none of operators allows to clearly highlight the superiority of a method, except for convergence rapidity and Jacobian.

Paper Details

Date Published: 29 April 2005
PDF: 9 pages
Proc. SPIE 5747, Medical Imaging 2005: Image Processing, (29 April 2005); doi: 10.1117/12.594906
Show Author Affiliations
Vlad Boldea, LIRIS, Univ. Lumiere Lyon 2 (France)
David Sarrut, LIRIS, Univ. Lumiere Lyon 2 (France)
Ctr. Leon-Berard (France)
Christian Carrie, Ctr. Leon-Berard (France)

Published in SPIE Proceedings Vol. 5747:
Medical Imaging 2005: Image Processing
J. Michael Fitzpatrick; Joseph M. Reinhardt, Editor(s)

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