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Proceedings Paper

Spectral-autofluorescent diagnostics of stomach and lung cancer
Author(s): Victor B. Loschenov; M. V. Baryshev; M. I. Kuzin; Victor Ya. Zavodnov; L. V. Uspensky; U. A. Ablitsov; L. E. Loginov; V. K. Rybin
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Paper Abstract

The results of investigations connected with stomach and lung cancerous tissue diagnostics and identification with a laser-endoscope spectroanalyzer are presented in this paper. Spectral measurements were carried out with endoscopy during surgery and after ektomy. It has been known since the beginning of this century that tumors have specific red fluorescence under UV light. We used this fact as a diagnostic criterion. However, we concluded that the most effective method of sensitive and reliable diagnostics was based on the simultaneous registration and scattering of autofluorescence from laser light applied for excitation. It should be noted that fluorescence is excited and registrated in the red spectral range. Application of this method allows for the identification of malignant lung and stomach tumors, as well as cancerous disease parabronchial or undermucousal tumors which can be inaccessible with known endoscopy procedures. The method also makes it possible to distinguish malignant and benign tumors. The relative simplicity and low cost of this technique allow the hope of good clinical applications in the near future.

Paper Details

Date Published: 6 May 1992
PDF: 16 pages
Proc. SPIE 1641, Physiological Monitoring and Early Detection Diagnostic Methods, (6 May 1992); doi: 10.1117/12.59378
Show Author Affiliations
Victor B. Loschenov, Moscow Medical Academy (Russia)
M. V. Baryshev, General Physics Institute (Russia)
M. I. Kuzin, Moscow Medical Academy (Russia)
Victor Ya. Zavodnov, General Physics Institute (Russia)
L. V. Uspensky, General Physics Institute (Russia)
U. A. Ablitsov, General Physics Institute (Russia)
L. E. Loginov, General Physics Institute (Russia)
V. K. Rybin, General Physics Institute (Russia)


Published in SPIE Proceedings Vol. 1641:
Physiological Monitoring and Early Detection Diagnostic Methods
Thomas S. Mang, Editor(s)

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