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Proceedings Paper

Time-domain optical mammography Softscan: initial results on detection and characterization of breast tumors
Author(s): Xavier Intes; Salim Djeziri; Zahia Ichalalene; Niculae Mincu; Yong Wang; Philippe St.-Jean; Frédéric Lesage; David Hall; David A. Boas; Margaret Polyzos
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Paper Abstract

Near-infrared (NIR) technology appears promising as a non-invasive clinical technique for breast cancer screening and diagnosis. The technology capitalizes on the relative transparency of human tissue in this spectral range and its sensitivity to the main components of the breast: water, lipid and hemoglobin. In this work we present initial results obtained using the SoftScan® breast-imaging system developed by ART, Advanced Research Technologies inc., Montreal. This platform consists of a 4-wavelength time-resolved scanning system used to quantify non-invasively the local functional state of breast tissue. The different aspects of the system used to accurately retrieve 3D optical contrast will be presented. Furthermore, preliminary data obtained from a prospective study conducted at The Royal Victoria Hospital of the McGill University Health Center in Montreal will be presented. During this study, 65 volunteers with either abnormal or normal mammograms were enrolled. Analysis of the data gathered by SoftScan demonstrated the potential of the technology in discriminating between healthy and diseased tissue.

Paper Details

Date Published: 9 December 2004
PDF: 10 pages
Proc. SPIE 5578, Photonics North 2004: Photonic Applications in Astronomy, Biomedicine, Imaging, Materials Processing, and Education, (9 December 2004); doi: 10.1117/12.593755
Show Author Affiliations
Xavier Intes, ART Advanced Research Technologies Inc. (Canada)
Salim Djeziri, ART Advanced Research Technologies Inc. (Canada)
Zahia Ichalalene, ART Advanced Research Technologies Inc. (Canada)
Niculae Mincu, ART Advanced Research Technologies Inc. (Canada)
Yong Wang, ART Advanced Research Technologies Inc. (Canada)
Philippe St.-Jean, ART Advanced Research Technologies Inc. (Canada)
Frédéric Lesage, ART Advanced Research Technologies Inc. (Canada)
David Hall, Univ. of California/San Diego (United States)
David A. Boas, Massachusetts General Hospital and Harvard Medical School (United States)
Margaret Polyzos, ART Advanced Research Technologies Inc. (Canada)


Published in SPIE Proceedings Vol. 5578:
Photonics North 2004: Photonic Applications in Astronomy, Biomedicine, Imaging, Materials Processing, and Education

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