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Proceedings Paper

High-resolution second harmonic optical coherence tomography
Author(s): Yi Jiang; Ivan V. Tomov; Yimin Wang; Zhongping Chen
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Paper Abstract

A high-resolution Second Harmonic Optical Coherence Tomography (SH-OCT) system is demonstrated using a spectrum broadened femtosecond Ti:sapphire laser. An axial resolution of 4.2 μm at the second harmonic wave center wavelength of 400 nm has been achieved. Because the SH-OCT system uses the second harmonic generation signals that strongly depend on the orientation, polarization and local symmetry properties of chiral molecules, this technique provides unique contrast enhancement to conventional optical coherence tomography. The system is applied to image biological tissues like the rat-tail tendon. Images of highly organized collagen fibrils in the rat-tail tendon have been demonstrated.

Paper Details

Date Published: 13 April 2005
PDF: 6 pages
Proc. SPIE 5690, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine IX, (13 April 2005); doi: 10.1117/12.591879
Show Author Affiliations
Yi Jiang, Univ. of California/Irvine (United States)
Ivan V. Tomov, Univ. of California/Irvine (United States)
Yimin Wang, Univ. of California/Irvine (United States)
Zhongping Chen, Univ. of California/Irvine (United States)


Published in SPIE Proceedings Vol. 5690:
Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine IX
Valery V. Tuchin; Joseph A. Izatt; James G. Fujimoto, Editor(s)

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