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Proceedings Paper

Three-dimensional retinal imaging with ultrahigh resolution, spectral domain optical coherence tomography
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Paper Abstract

Ultrahigh resolution OCT using broadband light sources achieves improved axial image resolutions of ~2-3 um compared to standard 10 um resolution OCT used in current commercial instruments. High-speed OCT using Fourier/spectral domain detection enables dramatic increases in imaging speeds. 3D OCT retinal imaging is performed in human subjects using high-speed, ultrahigh resolution OCT, and the concept of an OCT fundus image is introduced. Three-dimensional data and high quality cross-sectional images of retinal pathologies are presented. These results show that 3D OCT may be used to improve coverage of the retina, precision of cross-sectional image registration, quality of cross-sectional images, and visualization of subtle changes in retinal topography. 3D OCT imaging and mapping promise to help elucidate the structural changes associated with retinal disease as well as to improve early diagnosis and monitoring of disease progression and response to treatment.

Paper Details

Date Published: 18 April 2005
PDF: 10 pages
Proc. SPIE 5688, Ophthalmic Technologies XV, (18 April 2005); doi: 10.1117/12.591367
Show Author Affiliations
Vivek J. Srinivasan, Massachusetts Institute of Technology (United States)
Maciej Wojtkowski, Massachusetts Institute of Technology (United States)
Tufts Univ. School of Medicine (United States)
Nicolaus Copernicus Univ. (Poland)
Tony Ko, Massachusetts Institute of Technology (United States)
Mariana Carvalho, Massachusetts Institute of Technology (United States)
James G. Fujimoto, Massachusetts Institute of Technology (United States)
Jay S. Duker, Tufts Univ. School of Medicine (United States)
Joel S. Schuman, Univ. of Pittsburgh (United States)
Andrzej Kowalczyk, Nicholas Copernicus Univ. (Poland)

Published in SPIE Proceedings Vol. 5688:
Ophthalmic Technologies XV
Fabrice Manns; Bruce E. Stuck; Michael Belkin; Per G. Söderberg; Arthur Ho, Editor(s)

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