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Proceedings Paper

Near-infrared spectroscopic imaging of stimulus-related hemodynamic responses on the neonatal auditory cortices
Author(s): Kalle Kotilahti; Ilkka Nissila; Riikka Makela; Tommi Noponen; Lauri Lipiainen; Nasia Gavrielides; Timo Kajava; Minna Huotilainen; Vineta Fellman; Pekka Merilainen; Toivo Katila
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Paper Abstract

We have used near-infrared spectroscopy (NIRS) to study hemodynamic auditory evoked responses on 7 full-term neonates. Measurements were done simultaneously above both auditory cortices to study the distribution of speech and music processing between hemispheres using a 16-channel frequency-domain instrument. The stimulation consisted of 5-second samples of music and speech with a 25-second silent interval. In response to stimulation, a significant increase in the concentration of oxygenated hemoglobin ([HbO2]) was detected in 6 out of 7 subjects. The strongest responses in [HbO2] were seen near the measurement location above the ear on both hemispheres. The mean latency of the maximum responses was 9.42±1.51 s. On the left hemisphere (LH), the maximum amplitude of the average [HbO2] response to the music stimuli was 0.76± 0.38 μ M (mean±std.) and to the speech stimuli 1.00± 0.45 μ± μM. On the right hemisphere (RH), the maximum amplitude of the average [HbO2] response was 1.29± 0.85 μM to the music stimuli and 1.23± 0.93 μM to the speech stimuli. The results indicate that auditory information is processed on both auditory cortices, but LH is more concentrated to process speech than music information. No significant differences in the locations and the latencies of the maximum responses relative to the stimulus type were found.

Paper Details

Date Published: 28 April 2005
PDF: 8 pages
Proc. SPIE 5693, Optical Tomography and Spectroscopy of Tissue VI, (28 April 2005); doi: 10.1117/12.590180
Show Author Affiliations
Kalle Kotilahti, Helsinki Univ. of Technology (Finland)
Univ. of Helsinki (Finland)
Helsinki Univ. Central Hospital (Finland)
Ilkka Nissila, Helsinki Univ. of Technology (Finland)
Univ. of Helsinki (Finland)
Helsinki Univ. Central Hospital (Finland)
Riikka Makela, Univ. of Helsinki (Finland)
Helsinki Univ. of Technology (Finland)
Tommi Noponen, Helsinki Univ. of Technology (Finland)
Univ. of Helsinki (Finland)
Helsinki Univ. Central Hospital (Finland)
Lauri Lipiainen, Helsinki Univ. of Technology (Finland)
Univ. of Helsinki (Finland)
Helsinki Univ. Central Hospital (Finland)
Nasia Gavrielides, Univ. of Helsinki (Finland)
Helsinki Univ. of Technology (Finland)
Timo Kajava, Helsinki Univ. of Technology (Finland)
Minna Huotilainen, Univ. of Helsinki (Finland)
Vineta Fellman, Lund Univ. (Sweden)
Helsinki Univ. Central Hospital (Finland)
Pekka Merilainen, Helsinki Univ. of Technology (Finland)
Toivo Katila, Helsinki Univ. of Technology (Finland)
Univ. of Helsinki (Finland)
Helsinki Univ. Central Hospital (Finland)


Published in SPIE Proceedings Vol. 5693:
Optical Tomography and Spectroscopy of Tissue VI
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva M. Sevick-Muraca, Editor(s)

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