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Proceedings Paper

Bulk tissue optical parameters of porcine skin dermis at 8 wavelengths from 325 to 1550nm
Author(s): Xiaoyan Ma; Huafeng Ding; Jun Q. Lu; Kenneth M. Jacobs; Yousu Sun; Xin-Hua Hu
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Paper Abstract

Investigation of tissue optics requires accurate values of the bulk optical parameters: the scattering coefficient μs, absorption coefficient μa, anisotropy factor g and the real refractive index nr. We employed a coherent reflectance curve method to determine the refractive index of fresh porcine skin dermis at 8 wavelengths between 325 and 1557nm. The surface profiles of fresh dermis samples were measured with a non-contact method of confocal imaging and the roughness parameters were extracted. To determine tissue optical parameters, a single integrating sphere was used to measure the diffused reflectance and transmittance with slab samples of fresh porcine skin dermis. Collimated transmittance was measured with the samples in situ using a spatial filtering setup. Based on these results, a Monte Carlo code capable of handling surface roughness of the tissue sample has been developed and used to inversely determine the bulk values of μs, μa and g at the 8 wavelengths which are significantly different from the reported values.

Paper Details

Date Published: 15 April 2005
PDF: 8 pages
Proc. SPIE 5695, Optical Interactions with Tissue and Cells XVI, (15 April 2005); doi: 10.1117/12.589647
Show Author Affiliations
Xiaoyan Ma, East Carolina Univ. (United States)
Huafeng Ding, East Carolina Univ. (United States)
Jun Q. Lu, East Carolina Univ. (United States)
Kenneth M. Jacobs, East Carolina Univ. (United States)
Yousu Sun, Brody School of Medicine/East Carolina Univ. (United States)
Xin-Hua Hu, East Carolina Univ. (United States)


Published in SPIE Proceedings Vol. 5695:
Optical Interactions with Tissue and Cells XVI
Steven L. Jacques; William P. Roach, Editor(s)

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