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Proceedings Paper

Hemodynamic variations measured with near-infrared spectroscopy in human forearm muscles in response to venous occlusion: an electrical model
Author(s): Vo Van Toi; Matthew L. Hoimes; Shalini Nadgir; Sergio Fantini
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Paper Abstract

We present data collected with near-infrared spectroscopy on the human forearm (brachioradialis muscle) to characterize the hemodynamic response to venous occlusion in muscle. Venous occlusion was achieved in the upper arm by inflating a pneumatic cuff to a pressure of 60 mmHg. We performed absolute measurements of concentration and oxygen saturation of hemoglobin on six healthy adult human subjects. On all six subjects, we consistently found that during a 40-s venous occlusion the hemoglobin concentration increases (by 5.6±2.3 μM), while the oxygen saturation of hemoglobin decreases (by 2.1±0.7%). This accumulation and desaturation of blood in the forearm in response to the upper arm occlusion can be described with an electrical model in which the charge stored by a capacitor represents the local blood volume, and the electrical current represents blood flow.

Paper Details

Date Published: 28 April 2005
PDF: 8 pages
Proc. SPIE 5693, Optical Tomography and Spectroscopy of Tissue VI, (28 April 2005); doi: 10.1117/12.589302
Show Author Affiliations
Vo Van Toi, Tufts Univ. (United States)
Matthew L. Hoimes, Tufts Univ. (United States)
Shalini Nadgir, Tufts Univ. (United States)
Sergio Fantini, Tufts Univ. (United States)

Published in SPIE Proceedings Vol. 5693:
Optical Tomography and Spectroscopy of Tissue VI
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva M. Sevick-Muraca, Editor(s)

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