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Proceedings Paper

Integrated photonic system for optical imaging and spectroscopy: non-invasive monitoring of brain tumor (glioblastoma) angiogenesis
Author(s): Vishal Saxena; Jon F. Nielsen; Walter Laug; Marvin Nelson
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Paper Abstract

In this paper we describe a novel integrated photonic system that can be applied for optical imaging of intracranial brain tumor (Glioblastoma) angiogenesis in small animal model. A non-invasive multi-modality approach based on near infrared spectroscopy (NIRS) technique namely: Steady State Diffuse Optical Spectroscopy (DOS) along with Magnetic Resonance Imaging (MRI) technique is applied for monitoring the concentration of oxyhemoglobin, deoxyhemoglobin and water within tumor region and for studying the vascular status of tumor and the physiological changes that occur during brain tumor angiogenesis.

Paper Details

Date Published: 28 April 2005
PDF: 8 pages
Proc. SPIE 5693, Optical Tomography and Spectroscopy of Tissue VI, (28 April 2005); doi: 10.1117/12.588720
Show Author Affiliations
Vishal Saxena, Children's Hospital Los Angeles (United States)
Univ. of Southern California (United States)
Jon F. Nielsen, Children's Hospital Los Angeles (United States)
Walter Laug, Children's Hospital Los Angeles (United States)
Marvin Nelson, Children's Hospital Los Angeles (United States)


Published in SPIE Proceedings Vol. 5693:
Optical Tomography and Spectroscopy of Tissue VI
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva M. Sevick-Muraca, Editor(s)

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