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Proceedings Paper

The analysis of optical signals in response to various cells using a microflow cell cytometry
Author(s): Insoo Byun; Sunghyun Kim; Yiseok Kim; Jooran Yang; Sekwang Park
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Paper Abstract

The fabricated system is advantageous due to its low cost and simple structure. This is possible because it replaces many optical lenses and expensive equipment with optical fibers. We tested various optical fibers to select a suitable fiber for effective micro flow cell cytometry. In order to align between micro nozzle and optical fibers, a guide channel was fabricated by Si wafer etching with MEMS (Micro Electro-Mechanical System) technology. The micro flow cell cytometry using optical science and MEMS technology. The optical science using multi mode optical fiber and He-Ne laser (20mW, 658nm). The guide channel was fabricated by MEMS technology. The output voltage was as high as about 300 mV, so we are going to use a light source which has relatively small output power. By injecting various cells, we were able to detect cells. In addition, we can use the micro flow cell cytometry for analyzing cells (1, 2). We have no doubt that this micro flow cell cytometry can contribute to the development of biological engineering and clinical testing and it can be practically used in diagnoses of particular diseases and biological symptoms and invitro diagnostics (7, 8).

Paper Details

Date Published: 22 January 2005
PDF: 8 pages
Proc. SPIE 5718, Microfluidics, BioMEMS, and Medical Microsystems III, (22 January 2005); doi: 10.1117/12.586147
Show Author Affiliations
Insoo Byun, Kyungpook National Univ. (South Korea)
Sunghyun Kim, Kyungpook National Univ. (South Korea)
Yiseok Kim, Kyungpook National Univ. (South Korea)
Jooran Yang, Kyungpook National Univ. (South Korea)
Sekwang Park, Kyungpook National Univ. (South Korea)

Published in SPIE Proceedings Vol. 5718:
Microfluidics, BioMEMS, and Medical Microsystems III
Ian Papautsky; Isabelle Chartier, Editor(s)

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