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Proceedings Paper

Polymer microfluidic device replacing fluids using only capillary force
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Paper Abstract

A novel polymer microfluidic device for self-wash using only capillary force is presented. A liquid filled in a reaction chamber is replaced by another liquid with no external actuation. All the fluidic actuations in the device is pre-programmed about time and sequence, and accomplished by capillary force naturally. Careful design is necessary for exact actions. The fluidic conduits were designed by the newly derived theoretical equations about the capillary stop pressure and flow time. Simulations using CFD-ACE+ were conducted to check the validity of theory and the performance of the chip. These analytic results were consistent with experimental ones. The chip was made of polymers for the purpose of single use and low price. It was fabricated by sealing the hot-embossed PMMA substrate with a PET film. For simpler fabrication, the chip was of a single height. The embossing master was produced from a nickel-electroplating on a SU8-patterned Ni-plate followed by CMP. The contact angles of liquids on substrates were manipulated through the mixing of surfactants, and the temporal variations were monitored for a more exact design. The real actuation steps in experiment revealed the stable performance of selfwash, and coincided well with the designed ones. The presented microfluidic method can be applicable to other LOCs of special purposes through simple modification. For example, array or serial types would be possible for multiple selfwashes.

Paper Details

Date Published: 16 February 2005
PDF: 10 pages
Proc. SPIE 5651, Biomedical Applications of Micro- and Nanoengineering II, (16 February 2005); doi: 10.1117/12.582277
Show Author Affiliations
Kwang Hyo Chung, Electronics and Telecommunications Research Institute (South Korea)
Dae Sik Lee, Electronics and Telecommunications Research Institute (South Korea)
Haesik Yang, Electronics and Telecommunications Research Institute (South Korea)
Sung Jin Kim, Electronics and Telecommunications Research Institute (South Korea)
Hyun Bong Pyo, Electronics and Telecommunications Research Institute (South Korea)


Published in SPIE Proceedings Vol. 5651:
Biomedical Applications of Micro- and Nanoengineering II
Dan V. Nicolau, Editor(s)

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