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Gene network analysis and design
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Paper Abstract

Gene networks are composed of many different interacting genes and gene products (RNAs and proteins). They can be thought of as switching regions in n-dimensional space or as mass-balanced signaling networks. Both approaches allow for describing gene networks with the limited quantitative or even qualitative data available. We show how these approaches can be used in modeling the apoptosis gene network that has a vital role in tumor development. The open question is whether engineering changes to this network could be used as a possible cancer treatment.

Paper Details

Date Published: 16 February 2005
PDF: 8 pages
Proc. SPIE 5651, Biomedical Applications of Micro- and Nanoengineering II, (16 February 2005); doi: 10.1117/12.582096
Show Author Affiliations
Matthew J. Berryman, The Univ. of Adelaide (Australia)
Andrew Allison, The Univ. of Adelaide (Australia)
Derek Abbott, The Univ. of Adelaide (Australia)

Published in SPIE Proceedings Vol. 5651:
Biomedical Applications of Micro- and Nanoengineering II
Dan V. Nicolau, Editor(s)

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