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Proceedings Paper

Imaging cellular microtubules with the atomic-force microscope
Author(s): Brenda L. Dixon Northern; Mary Ann Jordan; Leslie Wilson; Joseph A. N. Zasadzinski
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Paper Abstract

We have immobilized chemically-fixed cellular microtubules and microtubule protein polymers on glow-discharged glass discs for scanning by atomic force microscopy (AFM). The images obtained by AFM resembled those obtained by conventional transmission electron microscopy of the same material. The AFM images can resolve some of the surface features of microtubules to 10 nm. Improvements in the techniques promise resolution approaching molecular dimensions.

Paper Details

Date Published: 1 May 1992
PDF: 7 pages
Proc. SPIE 1639, Scanning Probe Microscopies, (1 May 1992); doi: 10.1117/12.58193
Show Author Affiliations
Brenda L. Dixon Northern, Univ. of California/Santa Barbara (United States)
Mary Ann Jordan, Univ. of California/Santa Barbara (United States)
Leslie Wilson, Univ. of California/Santa Barbara (United States)
Joseph A. N. Zasadzinski, Univ. of California/Santa Barbara (United States)

Published in SPIE Proceedings Vol. 1639:
Scanning Probe Microscopies
Srinivas Manne, Editor(s)

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