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Proceedings Paper

Development of a multiphoton laser-induced fluorescence diagnosis system for microbiological and tissue applications
Author(s): Georgi Borislawow Graschew; Matthias Bastian; Stefan Rakowsky; Theo A. Roelofs; Evangelos Balanos; Peter M. Schlag
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Paper Abstract

Multiphoton excitation of selected dye molecules for laser-induced fluorescence diagnosis (LIFD) and optical biopsy of biological tissue and microbiological samples has various advantages: greater tissue penetration, more spatial resolution and less photo-bleaching. New applicators and microscopical set-ups for the delivery of the fs-pulsed laser radiation as required for multiphoton LIFD and optical biopsy need to be developed. Beam delivery solutions and workplaces for microbiological and tissue diagnosis are presented.

Paper Details

Date Published: 23 December 2004
PDF: 4 pages
Proc. SPIE 5620, Solid State Laser Technologies and Femtosecond Phenomena, (23 December 2004); doi: 10.1117/12.579510
Show Author Affiliations
Georgi Borislawow Graschew, Charite-Univ. Medicine Berlin (Germany)
Matthias Bastian, Charite-Univ. Medicine Berlin (Germany)
Stefan Rakowsky, Charite-Univ. Medicine Berlin (Germany)
Theo A. Roelofs, Charite-Univ. Medicine Berlin (Germany)
Evangelos Balanos, Charite-Univ. Medicine Berlin (Germany)
Peter M. Schlag, Charite-Univ. Medicine Berlin (Germany)

Published in SPIE Proceedings Vol. 5620:
Solid State Laser Technologies and Femtosecond Phenomena
Jonathan A. C. Terry; W. Andrew Clarkson, Editor(s)

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