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Proceedings Paper

Study on measurement interaction force on living cell by atomic force microscopy
Author(s): Yanxia Wang; Yanning Li; Xing Fu; Jun-Yong Cui; Xiaotang Hu
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Paper Abstract

A theoretical and experimental investigation of the force-distance relation in the case between a pyramidal tip and a cell is presented. The shape of the tip in use consists of a truncated pyramid covered by a spherical cap. The interaction force is computed the total interaction between macroscopic bodies. The experimental method is depicted in detail. The experimental results are comparison with the theory. The mechanical properties of the cell can be determined accurately and spatially well resolved from interaction force of tip-cell in AFM.

Paper Details

Date Published: 9 February 2005
PDF: 6 pages
Proc. SPIE 5635, Nanophotonics, Nanostructure, and Nanometrology, (9 February 2005); doi: 10.1117/12.577258
Show Author Affiliations
Yanxia Wang, Tianjin Univ. (China)
Yanning Li, Tianjin Univ. (China)
Xing Fu, Tianjin Univ. (China)
Jun-Yong Cui, Qingdao Mesnac Co. Ltd. (China)
Xiaotang Hu, Tianjin Univ. (China)


Published in SPIE Proceedings Vol. 5635:
Nanophotonics, Nanostructure, and Nanometrology
Xing Zhu; Stephen Y. Chou; Yasuhiko Arakawa, Editor(s)

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