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Proceedings Paper

Physiological meaning of cerebral oxygen saturation for piglet with hypoxia-ischemia
Author(s): Haishu Ding; Lan Huang; Chungchien Jen; Betau Hwang; Zhiguang Lee; Yichao Teng; Meizhi Zheng
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Paper Abstract

The physiological meaning of cerebral oxygen saturation absolute values and the oxygen metabolism of piglet with hypoxia-ischemia (HIE) were researched. The subjects were two piglets. During the total experiment of hypoxia then recovery, the regional cerebral tissue oxygen (rScO2), pulse oxygen saturation (SpO2) were detected non-invasively and the jugular oxygen saturation (SjO2), arterial oxygen saturation (SaO2) were given invasively. The results show that because SjO2 was equal to or larger than rScO2 and SaO2 > ScO2, rScO2 cannot be determined by the weighted sum of SjO2 and SaO2 which had been presented in some papers. According to above-mentioned analysis, the ecchymoma and pathological changes of the vessels due to HIE may be another contribution of rScO2. SjO2 was correlated with SaO2 (R=0.996 and 0.962 for two piglets) and the values of (SaO2-SjO2) are close to constants (29.3±8% and 30.3±8%).It means that because the subjects were under anesthesia, the oxygen consumption of cerebral tissue kept constants.

Paper Details

Date Published: 18 January 2005
PDF: 9 pages
Proc. SPIE 5630, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II, (18 January 2005); doi: 10.1117/12.575936
Show Author Affiliations
Haishu Ding, Tsinghua Univ. (China)
Lan Huang, Tsinghua Univ. (China)
Chungchien Jen, Taipei Veterans General Hospital (Taiwan)
Yang Ming Univ. (Taiwan)
Betau Hwang, Taipei Veterans General Hospital (Taiwan)
Yang Ming Univ. (Taiwan)
Zhiguang Lee, Shenzhen Peoples Hospital (China)
Yichao Teng, Tsinghua Univ. (China)
Meizhi Zheng, Taipei Veterans General Hospital (Taiwan)
Yang Ming Univ. (Taiwan)


Published in SPIE Proceedings Vol. 5630:
Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II
Britton Chance; Mingzhe Chen; Arthur E. T. Chiou; Qingming Luo, Editor(s)

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