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Proceedings Paper

The mechanism of electrostatic interaction between biological molecules and nanometal colloid on near-infrared surface-enhanced Raman scattering
Author(s): Haiying Zhao; Xiaoming Dou
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Paper Abstract

This paper reports effects of electrostatic interaction between amino acid and gold colloid on the intensity of surface-enhanced raman scattering (SERS). Near-infrared (NIR) excited SERS has been measured for lysine (Lys) on gold colloid at pH 10.8 and 12.0 where its ε-amino group is ionized and both the α- and ε-amino groups are neutralized, respectively. Note that the SERS intensity changes dramatically with pH. This result suggests that the electrostatic interaction between the positive charge of the ε-NH3+ group and the negative charge of the gold surface is one of the most important factors that determine the intensities of the SERS signals.

Paper Details

Date Published: 18 January 2005
PDF: 6 pages
Proc. SPIE 5630, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II, (18 January 2005); doi: 10.1117/12.575721
Show Author Affiliations
Haiying Zhao, Shanghai Jiaotong Univ. (China)
Xiaoming Dou, Shanghai Jiaotong Univ. (China)


Published in SPIE Proceedings Vol. 5630:
Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II
Britton Chance; Mingzhe Chen; Arthur E. T. Chiou; Qingming Luo, Editor(s)

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