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Proceedings Paper

Intracellular location, picosecond kinetics, and light-induced reactions of photosensitizing porphyrins
Author(s): Herbert Schneckenburger; Harold K. Seidlitz; Jurina M. Wessels; Angelika C. Rueck
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Paper Abstract

Porphyrin monomers dimers and aggregates with various tumour-localizing and photosensitizing properties can be differentiated on the basis of their fluorescence lifetimes. These individual components are shown to possess different degrees of polarization. This fact could be used for their microscopic imaging as well as for measurements of porphyrin coupling within cells and tissues. The spectral bands around 635 nm and 675 nm were correlated with the emission of porphyrin monomers and aggregates respectively. The formation of photo-protoporphyrin was not significant during the light-induced porphyrin reaction.

Paper Details

Date Published: 1 May 1991
PDF: 7 pages
Proc. SPIE 1403, Laser Applications in Life Sciences, (1 May 1991); doi: 10.1117/12.57320
Show Author Affiliations
Herbert Schneckenburger, Univ. Ulm (Germany)
Harold K. Seidlitz, Gesellschaft fuer Strahlen und Umweltforschung Muenchen (Germany)
Jurina M. Wessels, Gesellschaft fuer Strahlen und Umweltforschung Muenchen (Germany)
Angelika C. Rueck, Univ. Ulm (Germany)


Published in SPIE Proceedings Vol. 1403:
Laser Applications in Life Sciences

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