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Proceedings Paper

Laser-induced luminescence of singlet molecular oxygen: generation by drugs and pigments of biological importance
Author(s): Sergei Yu. Egorov; Alexander A. Krasnovsky Jr.
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Paper Abstract

The photon counting technique and flashlaser excitation were applied to the timeresolved measurement of photosensitized singlet oxygen luminescence in organic and aqueous media. The quantum yields for singlet oxygen generation have been measured in solutions of photosynthetic pigments synthetic and natural porphyrins porphyrins conjugated with monoclonal antibodies furocoumarins flavins fluorescein tetracycline and endogenous photosensitizers of human lens. The data obtained indicate that the measurement of the singlet oxygen luminescence is a reliable tool to study the photosensitizing activity of drugs and to elucidate primary mechanisms of photodynamic destruction. 1.

Paper Details

Date Published: 1 May 1991
PDF: 11 pages
Proc. SPIE 1403, Laser Applications in Life Sciences, (1 May 1991); doi: 10.1117/12.57282
Show Author Affiliations
Sergei Yu. Egorov, Moscow State Univ. (Russia)
Alexander A. Krasnovsky Jr., Moscow State Univ. (Russia)

Published in SPIE Proceedings Vol. 1403:
Laser Applications in Life Sciences
Sergei A. Akhmanov; Marina Yu. Poroshina, Editor(s)

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