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Proceedings Paper

A performance-optimized optical fiber bio-probe for cancerous tissue characterization
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Paper Abstract

Auto fluorescence of tissue depends not only on the concentration of fluoro-phores present in tissues but also on the configuration of optical fiber sensor. In this paper, feasibility of using laser induced fluorescence spectroscopy as a diagnostic tool for distinguishing malignant animal tissue from its normal counterpart under various design configurations is explored. Three different design configurations are tested for the performance optimization. The optimized Y-shaped optical reflection fiber probe gives the best laser induced fluorescence signal comparing to other probes. This instrument incorporated a continuous wave (CW) Nd:YAG laser operating at 532 nm.

Paper Details

Date Published: 14 December 2004
PDF: 5 pages
Proc. SPIE 5589, Fiber Optic Sensor Technology and Applications III, (14 December 2004); doi: 10.1117/12.571489
Show Author Affiliations
Chan Kyu Kim, Mississippi State Univ. (United States)
Sunil K. Khijwania, Indian Institute of Technology-Guwahati (India)
Jagdish P. Singh, Mississippi State Univ. (United States)

Published in SPIE Proceedings Vol. 5589:
Fiber Optic Sensor Technology and Applications III
Michael A. Marcus; Brian Culshaw; John P. Dakin, Editor(s)

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