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Proceedings Paper

Nanosensor for detection of glucose
Author(s): Ignacio Del Villar; Ignacio R. Matias; Francisco J. Arregui
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Paper Abstract

A novel fiber-optic sensor sensitive to glucose has been designed based on electrostatic self-assembly method. The polycation of the structure is a mixture of poly(allylamine hydrochloride) (PAH) and Prussian Blue, whereas the polyanion is well-known enzyme gluocose oxidase (GOx). The range of glucose concentration that can be measured is submilimolar and is located between 0.1 and 2 mM. Measures are based on a new detection scheme based on the slope of the change of signal produced by injection of glucose, yielding to a linear response. The sensor responses in a PH range between 4 and 7.4, which includes the physiological PH of blood. Some rules for esitmation of the refractive index of the material deposited and the thickness of bilayers are also given.

Paper Details

Date Published: 9 June 2004
PDF: 4 pages
Proc. SPIE 5502, Second European Workshop on Optical Fibre Sensors, (9 June 2004); doi: 10.1117/12.566547
Show Author Affiliations
Ignacio Del Villar, Univ. Publica de Navarra (Spain)
Ignacio R. Matias, Univ. Publica de Navarra (Spain)
Francisco J. Arregui, Univ. Publica de Navarra (Spain)


Published in SPIE Proceedings Vol. 5502:
Second European Workshop on Optical Fibre Sensors
Jose Miguel Lopez-Higuera; Brian Culshaw, Editor(s)

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