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Proceedings Paper

Structural analysis of DNA oligomers in single crystals and in aqueous solutions by micro-FTIR and Raman spectroscopy
Author(s): Heinz Fabian; W. Hoelzer; Dieter Naumann; H. Welfle; U. Heinemann
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Paper Abstract

Being interested in the effects of base sequence and environmental conditions on the DNA structure, we have analyzed the solution and crystal structures of some G/C-rich DNA oligomers by vibrational spectroscopy. Here, we report on the analysis of the octamer d(GGGATCCC) and the decamer d(CCAGGCCTGG). Raman spectra were recorded on a Raman spectrometer as in, infrared spectra were measured with a Fourier transform infrared spectrophotometer Bruker IFS-66, for infrared measurements on crystals, the IFS-66 was coupled to an IR-microscope.

Paper Details

Date Published: 1 March 1992
PDF: 2 pages
Proc. SPIE 1575, 8th Intl Conf on Fourier Transform Spectroscopy, (1 March 1992); doi: 10.1117/12.56445
Show Author Affiliations
Heinz Fabian, Central Institute of Molecular Biology (Germany)
W. Hoelzer, Pedagogic Univ. Erfurt (Germany)
Dieter Naumann, Robert Koch Institute of the Federal Health Office (Germany)
H. Welfle, Central Institute of Molecular Biology (Germany)
U. Heinemann, Free Univ. Berlin (Germany)

Published in SPIE Proceedings Vol. 1575:
8th Intl Conf on Fourier Transform Spectroscopy

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