Share Email Print
cover

Proceedings Paper

A polycapillary x-ray optics-based integrated micro-SPECT/CT scanner
Author(s): Steven M. Jorgensen; Michael S. Chmelik; Diane R. Eaker; Carolyn A. MacDonald; Erik Leo Ritman M.D.
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

To show the feasibility of a combined micro-CT and micro-SPECT scanner based on use of polycapillary optics we inserted an optic between the radio-labeled specimen and our micro-CT scanner's imaging system. The micro-CT x-ray focal spot was placed at the focal point of the optic so that x-ray micro-CT of the specimen could also be performed without having to move the specimen. Using this set-up we scanned a 2 cm diameter Plexiglas cylinder with three (177 μCi) prostate brachytherapy seeds embedded in it. Each seed was 0.5 mm diameter, 4 mm long and filled with 0.4 mm diameter ceramic beads coated with 125Iodine. The SPECT images clearly resolve the layer of 125Iodine on the beads. That the SPECT image is spatially correct was cofirmed by the concurrent CT image. We also used a parallel polycapillary optic to scan a 1.5 cm Plexiglas cylinder with holes (2, 1, and 0.5 mm diameter, parallel to the cylinder axis) filled with a solution containing 11.56μCi/mm3 of 125Iodine. These data indicate a spatial resolution of 5 line pairs per mm at 10% modulation. Based on these results we propose a design that is more efficient at acquiring the scintigraphic image data.

Paper Details

Date Published: 26 October 2004
PDF: 7 pages
Proc. SPIE 5535, Developments in X-Ray Tomography IV, (26 October 2004); doi: 10.1117/12.560991
Show Author Affiliations
Steven M. Jorgensen, Mayo Clinic College of Medicine (United States)
Univ. at Albany/SUNY (United States)
Michael S. Chmelik, Mayo Clinic College of Medicine (United States)
Univ. at Albany/SUNY (United States)
Diane R. Eaker, Mayo Clinic College of Medicine (United States)
Univ. at Albany/SUNY (United States)
Carolyn A. MacDonald, Mayo Clinic College of Medicine (United States)
Univ. at Albany/SUNY (United States)
Erik Leo Ritman M.D., Mayo Clinic College of Medicine (United States)
Univ. at Albany/SUNY (United States)


Published in SPIE Proceedings Vol. 5535:
Developments in X-Ray Tomography IV
Ulrich Bonse, Editor(s)

© SPIE. Terms of Use
Back to Top