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Proceedings Paper

Microphase-contrast x-ray computed tomography for basic biomedical study at SPring-8
Author(s): Jin Wu; Tohoru Takeda; Thet-Thet Lwin; Ichiro Koyama; Atsushi Momose; Akiko Fujii; Yoshitaka Hamaishi; Taichi Kuroe; Tetsuya Yuasa; Yoshio Suzuki; Takao Akatsuka
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Paper Abstract

Micro-phase-contrast X-ray computed tomography with an X-ray interferometer (micro-phase-contrast CT) is in operation to obtain high spatial resolution images of less than 0.01 mm at the undulator beam-line 20XU of SPring-8, Japan, and we applied micro-phase-contrast CT to observe the organs of rats and hamsters. The excised kidney and spleen fixed by formalin were imaged. The fine inner-structures such as vessels, glomeruli of kidney and white and red pulps of spleen were visualized clearly about 0.01-mm spatial resolutions without using contrast agent or staining procedure. The results were very similar to those by optical microscopic images with 20-fold magnification. These results suggest that the micro-phase tomography might be a useful tool for various biomedical researches.

Paper Details

Date Published: 26 October 2004
PDF: 8 pages
Proc. SPIE 5535, Developments in X-Ray Tomography IV, (26 October 2004); doi: 10.1117/12.559390
Show Author Affiliations
Jin Wu, Univ. of Tsukuba (Japan)
Tohoru Takeda, Univ. of Tsukuba (Japan)
Thet-Thet Lwin, Univ. of Tsukuba (Japan)
Ichiro Koyama, The Univ. of Tokyo (Japan)
Atsushi Momose, The Univ. of Tokyo (Japan)
Akiko Fujii, The Univ. of Tokyo (Japan)
Yoshitaka Hamaishi, The Univ. of Tokyo (Japan)
Taichi Kuroe, Yamagata Univ. (Japan)
Tetsuya Yuasa, Yamagata Univ. (Japan)
Yoshio Suzuki, SPring-8 (Japan)
Takao Akatsuka, Yamagata Univ. (Japan)


Published in SPIE Proceedings Vol. 5535:
Developments in X-Ray Tomography IV
Ulrich Bonse, Editor(s)

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