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Proceedings Paper

Shape deformations of giant unilamellar vesicles with a laser tweezer array
Author(s): Wolfgang Losert; Cory Poole; Peter Bradford; Doug English
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Paper Abstract

Vesicles are phospholipid bilayers that form a surface enclosing a volume of water or solution. They are of importance as model systems to study cells, as well as having practical applications such as containers for performing nanochemistry and facilitating drug delivery. Their properties have been studied for decades. Using a holographic laser tweezer array (LTA), which converts a single laser beam into many laser tweezer points, we stretch the vesicles in controlled ways from several points at once, measuring each force applied. Here, we present data on shape deformations of simple, spherical vesicles and on membrane fracture.

Paper Details

Date Published: 18 October 2004
PDF: 10 pages
Proc. SPIE 5514, Optical Trapping and Optical Micromanipulation, (18 October 2004); doi: 10.1117/12.557589
Show Author Affiliations
Wolfgang Losert, Univ. of Maryland/College Park (United States)
Cory Poole, Univ. of Maryland/College Park (United States)
Peter Bradford, Univ. of Maryland/College Park (United States)
Doug English, Univ. of Maryland/College Park (United States)

Published in SPIE Proceedings Vol. 5514:
Optical Trapping and Optical Micromanipulation
Kishan Dholakia; Gabriel C. Spalding, Editor(s)

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