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Proceedings Paper

Ionic current through an open channel: a low-dimensional model of coupling with vibrations of the wall
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Paper Abstract

Ionic motion through an open ion channel is analyzed within the framework of self-consistent Brownian dynamics formalism. A novel conceptual model of coupling of the ion's motion to the vibrations of the pore walls is introduced. The model allows one to include into simulations an important additional mechanism of energy dissipation and the effects of self-induced strong modulation of the channel conductivity.

Paper Details

Date Published: 25 May 2004
PDF: 7 pages
Proc. SPIE 5467, Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems II, (25 May 2004); doi: 10.1117/12.548573
Show Author Affiliations
Rodrigue Tindjong, Lancaster Univ. (United Kingdom)
Alan Applegate, Lancaster Univ. (United Kingdom)
Robert S. Eisenberg, Rush Medical College (United States)
Igor Kaufman, Russian Research Institute for Metrological Service (Russia)
Dimitry G. Luchinsky, Lancaster Univ. (United Kingdom)
Peter V. E. McClintock, Lancaster Univ. (United Kingdom)


Published in SPIE Proceedings Vol. 5467:
Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems II
Derek Abbott; Sergey M. Bezrukov; Andras Der; Angel Sanchez, Editor(s)

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