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Proceedings Paper

Spike sorting in networks of cultured neurons on multi-electrode arrays
Author(s): Ni Sun; Qingming Luo; Xiangning Li
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Paper Abstract

The technology of micro-electrode arrays is getting more and more important in the research of brain neural networks and its dynamics because of the ability to stimulate and record more neurons’ activities simultaneously. When the signals of many neurons with several noises in a local region are picked up with a microelectrode, a neurophysiologist may wish to sort these signals by assigning particular spikes to putative neurons with some degree of reliability. Spike sorting is a key step in whole data process and is a general problem in neural electrophysiology. Many algorithms for spike sorting have been brought forward based on the features of the spike waveforms from different neurons. In this article, I have accomplished spike sorting through analyzing the amplitude, shape and principal components of the spikes.

Paper Details

Date Published: 8 December 2003
PDF: 8 pages
Proc. SPIE 5254, Third International Conference on Photonics and Imaging in Biology and Medicine, (8 December 2003); doi: 10.1117/12.546560
Show Author Affiliations
Ni Sun, Huazhong Univ. of Science and Technology (China)
Qingming Luo, Huazhong Univ. of Science and Technology (China)
Xiangning Li, Huazhong Univ. of Science and Technology (China)


Published in SPIE Proceedings Vol. 5254:
Third International Conference on Photonics and Imaging in Biology and Medicine
Qingming Luo; Valery V. Tuchin; Min Gu; Lihong V. Wang, Editor(s)

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