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Proceedings Paper

Laser-induced human serum fluorescence and Raman spectroscopy detection of colon cancer
Author(s): Xiaozhou Li; Junxiu Lin; Chunyu Wu; Rong Wang; Yongkai Li; Chunde Jia
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Paper Abstract

Laser-induced fluorescence and Raman spectroscopy of serum for diagnostic colon cancer was investigated in this paper. The difference to serum spectrum was discovered. Three Raman peaks were consistently observed from normal blood serum emission using 488.0 nm and 514.5 nm excitation of an Ar-ior laser. While no Raman peak or slight Raman peaks were detected from colon cancer's cases. In addition, the red shift of fluorescence peak and decrease of fluorescence intensity are founded after samples radiated by laser. 120 colon cancer cases are investigated in this paper. Through three parameters we obtained an accuracy of 82.5% compared to clinical diagnosis. These results have important reference values to explore the method of Raman spectrum and LIF for diagnosis of cancer.

Paper Details

Date Published: 4 December 2003
PDF: 6 pages
Proc. SPIE 5255, Biomolecular Photonics and Multidimensional Microscopy, (4 December 2003); doi: 10.1117/12.546250
Show Author Affiliations
Xiaozhou Li, Dalian Univ. of Technology (China)
Liaoning Univ. (China)
Junxiu Lin, Dalian Univ. of Technology (China)
Chunyu Wu, Liaoning Univ. (China)
Rong Wang, Liaoning Univ. (China)
Yongkai Li, Liaoning Univ. (China)
Chunde Jia, Shenyang Institute of Technology (China)

Published in SPIE Proceedings Vol. 5255:
Biomolecular Photonics and Multidimensional Microscopy
Qingming Luo; Min Gu, Editor(s)

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