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Proceedings Paper

Optical intrinsic signals in rat primary somatosensory cortex during non-noxious and noxious electrical stimulation of the sciatic nerve
Author(s): Weihua Luo; Pengcheng Li; Shangbin Chen; Qingming Luo
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Paper Abstract

Optical imaging method was applied into observing the temporal-spatial characteristic of rat primary somatosensory cortex during graded electrical stimulation of the sciatic nerve (5hz,duration of 2s,0.5ms puls,1x,10x and 20x muscle twitch threshold). We found that the temporal and spatial properties of hindlimb somatosensory cortex were modulated by graded intensity electrical stimulation of the sciatic nerve. The magnitude and time course were larger and longer with the intensity raising. And the spatial extent was wider at 20x stimulus than the other two kinds of stimulus. Therefore, our optical imaging was based on 570nm, which only reflect the changes of blood volume. Then our future study will reveal more information of pain modulation in primary somatosensory cortex.

Paper Details

Date Published: 8 December 2003
PDF: 7 pages
Proc. SPIE 5254, Third International Conference on Photonics and Imaging in Biology and Medicine, (8 December 2003); doi: 10.1117/12.546230
Show Author Affiliations
Weihua Luo, Huazhong Univ. of Science and Technology (China)
Pengcheng Li, Huazhong Univ. of Science and Technology (China)
Shangbin Chen, Huazhong Univ. of Science and Technology (China)
Qingming Luo, Huazhong Univ. of Science and Technology (China)


Published in SPIE Proceedings Vol. 5254:
Third International Conference on Photonics and Imaging in Biology and Medicine
Qingming Luo; Valery V. Tuchin; Min Gu; Lihong V. Wang, Editor(s)

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