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Proceedings Paper

The membrane receptor mediated signal transduction mechanism of low-intensity light effects on fibroblast
Author(s): Yan Li; Timon Cheng-Yi Liu; Jian-Ling Jiao; An Hong; Songhao Liu
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Paper Abstract

The membrane receptor mediated signal transduction mechanism (STM) on photobiomodulation was suggested by Liu et al, and verified by successful applications. In this paper, it was used to study photobiomodulation on fibroblasts. As the frequency of the absorption light of membrane receptors is greater than the light from UVA to IR, the membrane absorption of the light is non-resonant, and its transition rate is extraordinarily small, but can be amplified by the coherent state of the identical and independent membrane receptors. The activation coherent states of receptors will activate signal transduction pathway, which was called collective phototransduction. It was shown that collective phototransduction mediated STM was one of the possible mechanisms of photobiomodulation on fibroblasts.

Paper Details

Date Published: 8 December 2003
PDF: 9 pages
Proc. SPIE 5254, Third International Conference on Photonics and Imaging in Biology and Medicine, (8 December 2003); doi: 10.1117/12.546118
Show Author Affiliations
Yan Li, South China Normal Univ. (China)
Timon Cheng-Yi Liu, South China Normal Univ. (China)
Huazhong Univ. of Science and Technology (China)
Jian-Ling Jiao, Jinan Univ. (China)
An Hong, Jinan Univ. (China)
Songhao Liu, South China Normal Univ. (China)


Published in SPIE Proceedings Vol. 5254:
Third International Conference on Photonics and Imaging in Biology and Medicine
Qingming Luo; Valery V. Tuchin; Min Gu; Lihong V. Wang, Editor(s)

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