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Proceedings Paper

Reactive chromophores for sensitive and selective detection of chemical warfare agents
Author(s): Greg Frye-Mason; Martin Leuschen; Marcus la Grone; Lara Wald; Craig Aker; Matt Dock; Lawrence F. Hancock; Steve Fagan; Kateri Paul
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Paper Abstract

A new sensor for highly toxic species including chemical warfare (CW) agents has been developed. This sensor is based on a unique CW indicating chromophore (CWIC) developed by Professor Tim Swager at MIT. The CWIC was designed to be sensitive to the reactivity that makes these chemicals so toxic. Since it requires the reactivity of the agent to be detected, the CWIC technology has shown remarkable selectivity for nerve agent surrogates and some other highly toxic species, thereby demonstrating the potential to provide low false alarm rate detection. Since the chromophore has mini-mal fluorescence prior to reaction with an electrophilic and toxic chemical, the sensor acts in a dark field fluorescence mode. This provides the sensor with exceptional sensitivity and a potential to detect priority analytes well below levels detected by current hand held sensors. Finally, it is based on a simple optical detection scheme that enables small and rugged sensors to be developed and produced at a low enough cost so they can be widely utilized.

Paper Details

Date Published: 13 August 2004
PDF: 9 pages
Proc. SPIE 5416, Chemical and Biological Sensing V, (13 August 2004); doi: 10.1117/12.542913
Show Author Affiliations
Greg Frye-Mason, Nomadics, Inc. (United States)
Martin Leuschen, Nomadics, Inc. (United States)
Marcus la Grone, Nomadics, Inc. (United States)
Lara Wald, Nomadics, Inc. (United States)
Craig Aker, Nomadics, Inc. (United States)
Matt Dock, Nomadics, Inc. (United States)
Lawrence F. Hancock, Nomadics, Inc. (United States)
Steve Fagan, Nomadics, Inc. (United States)
Kateri Paul, Nomadics, Inc. (United States)


Published in SPIE Proceedings Vol. 5416:
Chemical and Biological Sensing V
Patrick J. Gardner, Editor(s)

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