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Paper Abstract

A light microscope capable to show images of molecules in nanometer scale has been a dream of scientists, which, however, is difficult due to the strict limitation of spatial resolution due to the wave nature of light. While there have been attempts to overcome the diffraction limit by using nonlinear response of materials, near-field optical microscopy could provide better detecting accuracy. In this paper, we present molecular distribution nano-imaging colored by Raman-scattering spectral shifting, which is probed with a metallic tip. The metallic probe tip has been used to enhance the optical field only in the vicinity of probe tip. The effect is similar to the one seen in the detection of molecules on the metal-island film, known as surface-enhanced Raman spectroscopy (SERS), while in this case a single metallic tip works for the field enhancement in nanometer scale.

Paper Details

Date Published: 1 June 2004
PDF: 12 pages
Proc. SPIE 5331, Nanobiophotonics and Biomedical Applications, (1 June 2004); doi: 10.1117/12.537670
Show Author Affiliations
Satoshi Kawata, Osaka Univ. (Japan)
Japan Science and Technology Corp. (Japan)
The Institute of Physical and Chemical Research (RIKEN) (Japan)
Norihiko Hayazawa, Osaka Univ. (Japan)
Japan Science and Technology Corp. (Japan)
Takaaki Yano, Osaka Univ. (Japan)
Hiroyuki Watanabe, Osaka Univ. (Japan)
Taro Ichimura, Osaka Univ. (Japan)
Mamoru Hashimoto, Osaka Univ. (Japan)
Japan Science and Technology Corp. (Japan)
Yasushi Inouye, Osaka Univ. (Japan)
Japan Science and Technology Corp. (Japan)

Published in SPIE Proceedings Vol. 5331:
Nanobiophotonics and Biomedical Applications
Alexander N. Cartwright, Editor(s)

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