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Proceedings Paper

Preliminary system characterization of flat-panel-detector-based cone-beam CT for breast imaging
Author(s): Ruola Ning; Yong Yu; David L. Conover; Xianghua Lu; Huiguang He; Zikuan Chen; Linda Schiffhauer; Jeanne Cullinan
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Paper Abstract

Conventional film-screen mammography is the most effective tool for the early detection of breast cancer currently available. However, conventional mammography has relatively low sensitivity to detect small breast cancers (under several millimeters) owing to an overlap in the appearances of benign and malignant lesions, and surrounding structure. The limitations accompanying conventional mammography is to be addressed by incorporating a cone beam CT imaging technique with a recently developed flat panel detector. Computer simulation and preliminary studies have been performed to prove the feasibility of developing a flat panel detector-based cone beam CT breast imaging (FPD-CBCTBI) technique. A preliminary system characterization study of flat panel detector-based cone beam CT for breast imaging was performed to confirm the findings in the computer simulation and previous phantom studies using the current prototype cone beam CT scanner. The results indicate that the CBCTBI technique effectively removes structure overlap and significantly improves the detectability of small breast tumors. More importantly, the results also demonstrate CBCTBI offers good image quality with the radiation dose level less than or equal to that of conventional mammography. The results from this study suggest that FPD-CBCTBI is a potentially powerful breast-imaging tool.

Paper Details

Date Published: 6 May 2004
PDF: 12 pages
Proc. SPIE 5368, Medical Imaging 2004: Physics of Medical Imaging, (6 May 2004); doi: 10.1117/12.536231
Show Author Affiliations
Ruola Ning, Univ. of Rochester Medical Ctr. (United States)
Yong Yu, Univ. of Rochester Medical Ctr. (United States)
David L. Conover, Univ. of Rochester Medical Ctr. (United States)
Xianghua Lu, Univ. of Rochester Medical Ctr. (United States)
Huiguang He, Univ. of Rochester Medical Ctr. (United States)
Zikuan Chen, Univ. of Rochester Medical Ctr. (United States)
Linda Schiffhauer, Univ. of Rochester Medical Ctr. (United States)
Jeanne Cullinan, Univ. of Rochester Medical Ctr. (United States)


Published in SPIE Proceedings Vol. 5368:
Medical Imaging 2004: Physics of Medical Imaging
Martin J. Yaffe; Michael J. Flynn, Editor(s)

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