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Proceedings Paper

Improved automated brachytherapy seed localization in trans-urethral ultrasound data
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Paper Abstract

The utility of Trans-urethral ultrasound(TUUS) for permanent prostate brachytherapy is dependent on the quality of the data acquired. Previous work on Trans-urethral ultrasound suggested that TUUS acquires higher quality images than Trans-rectal ultrasound. Manual segmentation of TUUS data limits the utility of TUUS intra-operative, however, automated segmentation methods can be used to reduce the processing time. This research describes a segmentation paradigm which incorporates a priori information about the implanted seeds in order to provide a reasonable segmentation. The segmentation framework incorporates information about the size, shape, and orientation of the seeds. The paradigm integrates this information using fuzzy inference rules. The results show that the automated method is at least 4 times faster than manual segmentation. The sensitivity and specificity of the method were 76% and 93%, respectively. The decrease sensitivity is acceptable because it is the specificity which is more critical in determining if adequate dose has been delivered. Future work with this method will increase accuracy by incorporating additional information about the seeds.

Paper Details

Date Published: 5 May 2004
PDF: 8 pages
Proc. SPIE 5367, Medical Imaging 2004: Visualization, Image-Guided Procedures, and Display, (5 May 2004); doi: 10.1117/12.535865
Show Author Affiliations
David R. Holmes III, Mayo Clinic and Foundation (United States)
Richard A. Robb, Mayo Clinic and Foundation (United States)

Published in SPIE Proceedings Vol. 5367:
Medical Imaging 2004: Visualization, Image-Guided Procedures, and Display
Robert L. Galloway Jr., Editor(s)

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