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Proceedings Paper

Fast treatment planning with IVUS imaging in intravascular brachytherapy
Author(s): Raffaele Novario; Carla Bianchi; Rita Lorusso; Chiara Sampietro; Fabio Tanzi; Leopoldo Conte; Mario Vescovi; Massimo Caccia; Mario Alemi; Chiara Cappellini
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Paper Abstract

The planned target volume in intracoronary brachytherapy is the vessel wall. The success of the treatment is based on the need of delivering doses possibly not lower than 8 and not higher than 30 Gy. An automatic procedure in order to acquire intravascular ultrasound images of the whole volume to be irradiated is pointed out; a motor driven pullback device, with velocity of the catheter of 0.5 and 1 mm/s allows to acquire the entire target volume of the vessel with a number of slices normally ranging from 400 to 1600. A semiautomatic segmentation and classification of the different structures in each slice of the vessel is proposed. The segmentation and the classification of the structures allows the calculation of their volume; this is very useful in particular for plaque volume assessment in the follow-up of the patients. A 3D analyser tool was developed in order to visualize the walls and the lumen of the vessel. The knowledge, for each axial slice, of the position of the source (in the centre of the catheter) and the position of the target (vessel walls) allows the calculation of a set of source-target distances. Given a time of irradiation, and a type of source a dose volume histogram (DVH) describing the distribution of the doses in the whole target can be obtained. The whole procedure takes few minutes and then is compatible with a safe treatment of the patient, giving an important indication about the quality of the radiation treatment selected.

Paper Details

Date Published: 5 May 2004
PDF: 9 pages
Proc. SPIE 5367, Medical Imaging 2004: Visualization, Image-Guided Procedures, and Display, (5 May 2004); doi: 10.1117/12.534049
Show Author Affiliations
Raffaele Novario, Univ. Hospital Varese (Italy)
Carla Bianchi, Univ. Hospital Varese (Italy)
Rita Lorusso, Univ. Hospital Varese (Italy)
Chiara Sampietro, Univ. Hospital Varese (Italy)
Fabio Tanzi, Univ. Hospital Varese (Italy)
Leopoldo Conte, Univ. degli Studi dell'Insubria (Italy)
Mario Vescovi, Research Systems Inc. (Italy)
Massimo Caccia, Univ. degli Studi dell'Insubria (Italy)
Mario Alemi, Univ. degli Studi dell'Insubria (Italy)
Chiara Cappellini, Univ. degli Studi dell'Insubria (Italy)

Published in SPIE Proceedings Vol. 5367:
Medical Imaging 2004: Visualization, Image-Guided Procedures, and Display
Robert L. Galloway Jr., Editor(s)

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