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Proceedings Paper

A procedure for the evaluation of 2D radiographic texture analysis to assess 3D bone micro-architecture
Author(s): Lian Apostol; Francoise Peyrin; Sophie Yot; Olivier Basset; Christophe Odet; Joachim Tabary; Jean-Marc Dinten; Elodie Boller; Vincent Boudousq; Pierre-Olivier Kotzki
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Paper Abstract

Although the diagnosis of osteoporosis is mainly based on Dual X-ray Absorptiometry, it has been shown that trabecular bone micro-architecture is also an important factor in regards of fracture risk, which can be efficiently assessed in vitro using three-dimensional x-ray microtomography (μCT). In vivo, techniques based on high-resolution s-ray radiography associated to texture analysis have been proposed to investigate bone micro-architecture, but their relevance for giving pertinent 3D information is unclear. The purpose of this work was to develop a method for evaluating the relationships betweeen 3D micro-architecture and 2D texture parameters, and optimizing the conditions for radiographic imaging. Bone sample images taken from cortical to cortical were acquired using 3D-synchrotron x-ray μCT at the ESRF. The 3D digital imagees were further used for two purposes: 1) quantification of three-dimensional bone micro-architecture, 2) simulation of realistic x-ray radiographs under different acquisition conditions. Texture analysis was then applied to these 2D radiographs using a large variety of methods (co-occurence, spectrum, fractal...). First results of the statistical analysis between 2D and 3D parameters allowed identfying the most relevant 2D texture parameters.

Paper Details

Date Published: 12 May 2004
PDF: 12 pages
Proc. SPIE 5370, Medical Imaging 2004: Image Processing, (12 May 2004); doi: 10.1117/12.533452
Show Author Affiliations
Lian Apostol, CREATIS (France)
ESRF (France)
Francoise Peyrin, CREATIS (France)
ESRF (France)
Sophie Yot, CREATIS (France)
Olivier Basset, CREATIS (France)
Christophe Odet, CREATIS (France)
Joachim Tabary, LETI-CEA (France)
Jean-Marc Dinten, LETI-CEA (France)
Elodie Boller, ESRF (France)
Vincent Boudousq, CHU Nimes (France)
Pierre-Olivier Kotzki, CHU Nimes (France)


Published in SPIE Proceedings Vol. 5370:
Medical Imaging 2004: Image Processing
J. Michael Fitzpatrick; Milan Sonka, Editor(s)

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