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Proceedings Paper

Visualization of HIFU-induced lesions with thermoacoustic tomography
Author(s): Xing Jin; Yuan Xu; Lihong V. Wang; Claudio I. Zanelli; Samuel M. Howard; Yuncai Fang
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Paper Abstract

High-intensity focused ultrasound (HIFU) has proved to be an effective minimally invasive surgical technology. In this study, we focus on the visualization of HIFU-induced lesions using microwave-induced thermoacoustic tomography (TAT). TAT has high spatial resolution, comparable with ultrasound imaging, and high contrast, which is induced by differences in the microwave absorption rates between tumor tissue and normal tissue. TAT can, in addition, differentiate tumors before and after treatment. A single, spherically focused transducer operating at a center frequency of approximately 4 MHZ was used to generate the focused field. The lesion was generated in porcine muscle. A local-tomography-type reconstruction algorithm was applied to reconstruct the TAT image of the lesions. The lesion shown by gross pathology confirms the corresponding region measured by TAT.

Paper Details

Date Published: 12 July 2004
PDF: 4 pages
Proc. SPIE 5320, Photons Plus Ultrasound: Imaging and Sensing, (12 July 2004); doi: 10.1117/12.532359
Show Author Affiliations
Xing Jin, Texas A&M Univ. (United States)
Yuan Xu, Texas A&M Univ. (United States)
Lihong V. Wang, Texas A&M Univ. (United States)
Claudio I. Zanelli, Onda Corp. (United States)
Samuel M. Howard, Onda Corp. (United States)
Yuncai Fang, Onda Corp. (United States)

Published in SPIE Proceedings Vol. 5320:
Photons Plus Ultrasound: Imaging and Sensing
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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